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NOTÍCIAS - Modiodal
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Psychopharmacology for the Clinician Psychopharmacologie pratique
As shown by the clinical vignette, psychostimulants are being increasingly used as augmentation agents for conventional antidepressant drugs, particularly given their usually rapid onset of action (normally within 48 hr)
and relative lack of major side effects (Huffman and Stern, Prim Care Companion J Clin Psychiatry 2004;6:44-6).
The most commonly used stimulants are dextroamphetamine (10–40 mg/d) and methylphenidate (10–60 mg/d). Other more recent alternatives include atomoxetine (a selective norepinephrine reuptake inhibitor used in doses of 40–120 mg/d) and pramipexole (a dopamine D2/D3 receptor agonist used in doses of 0.25–1 mg 3 times daily).
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Modafinil for excessive sleepiness associated with chronic shift work sleep disorder: effects on patient functioning and health-related quality of life
Shift work sleep disorder (SWSD) ia a circadian rhythm sleep disorder that results from the inability of some shift workers to adapt to their major misalignment between the worfk-rest shedule imposed by their occupation and the internal rhytms that are normally responsible for the physiologic maintenance of sleep and wakefulness.
SWSD is characterized by symptoms of excessive sleepiness or insomnia, symtoms that can negatively impact daily living.
Excessive sleepiness has been shown to impair +erformance and quality of life, regardless od its underlying cause.
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